Much of the eastern half of the United States is bracing for severe weather this weekend, with “life-threatening” flash flooding possible in parts of the Southeast and significant snow set to blanket the Upper Midwest through to New England.

Much of the U.S. East endured a renewed round of harsh, soggy weather Saturday, as water submerged cars and buildings in Kentucky and mudslides blocked roads in Virginia. Forecasters predicted snowstorms in the Northeast and the threat of tornadoes for the Mississippi Valley.