Palladium-catalyzed arylation of carbonyl compounds constitutes a cornerstone of modern cross-coupling chemistry, enabling the direct formation of C(sp2)–C(sp3) bonds at the α-position of aldehydes, ...

The reaction utilizes an iron catalyst together with an N-heterocyclic carbene (NHC) ligand, which suppresses unwanted side reactions to promote highly selective nucleophile addition. In organic ...

Carbonyl compounds, characterised by a carbon–oxygen double bond, constitute a fundamental class of building blocks in organic synthesis. They are accessed through diverse routes including alcohol ...

Carbonyls (C=O groups) are popular reactive handles. But carbonylation reactions, which create these useful groups by appending carbon monoxide to aryl halides or alkyl halides with the help of a ...