During B and T lymphocyte development, antigen receptor diversity arises through V(D)J recombination, a process driven by the RAG1/2 endonuclease that introduces programmed double-stranded DNA breaks ...

B lymphocytes (or B cells) descend from bone marrow (BM) hematopoietic stem cells (HSC) and mediate humoral immunity by secreting antibodies. Early studies based on a selected set of surface and ...

Atypical lymphocytes are types of white blood cells that a person’s immune system produces. They help fight infections and diseases. High levels of atypical lymphocytes may indicate health issues.