Objective Inflammation and repair responses may be involved in atherosclerosis in rheumatoid arthritis (RA), although ...
Professor Alexander Hoffmann and Genhong Cheng from University of California, Los Angeles, jointly with Professor David ...
B-cell maturation antigen (BCMA) is encoded by the TNFRSF17 gene found on the short arm of chromosome 16. BCMA is a type III transmembrane glycoprotein primarily expressed on the surface of myeloma ...
In experiments with mouse models of breast, pancreatic, and muscle cancers, researchers at Johns Hopkins All Children's Hospital report new evidence that a novel means of boosting the natural immune ...
DESTIN, Fla. — An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according to a speaker at the Congress of Clinical Rheumatology East ...
Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced (armored) ...
The deubiquitinase USP17LA negatively regulates T-cell activation and attenuates anti-tumor immunity
USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...
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