“Interestingly, BIRC5 and MCL-1 have both been reported to be over-expressed and strongly correlated with progression and ...

Spread the loveIn a groundbreaking study, scientists have unveiled a previously unidentified characteristic of cell death that may revolutionize our understanding of the immune system and its response ...

(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...

Cancer’s deadliest talent is not rapid growth but the ability to sidestep the internal programs that should make damaged cells self-destruct. Across multiple labs, researchers are now converging on a ...

Now, in a study published March 30 in Cell Chemical Biology, UB scientists have shed light on one such stressor, showing that ...

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate ...

Researchers at St. Jude Children's Research Hospital have uncovered a new pathway for mitochondrial cell death that involves the protein BCL-2 ovarian killer, otherwise known as BOK. The discovery, ...

Researchers at National Jewish Health and collaborating institutions have uncovered a critical mechanism driving persistent ...

Ceramide buildup due to faulty transport triggers stress responses that lock cells into senescence, revealing a potential ...

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate.