Cancer cell death following genotoxic therapy is often attributed to excessive or unrepaired genome damage. However, emerging evidence suggests that the repair of DNA double-strand breaks, rather than ...

Northwestern Medicine investigators have discovered new mechanisms underlying cellular adhesion and repair, findings that could inform the development of new therapeutics that boost cellular repair ...

Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular viability. Because damage occurs non-uniformly across the genome, single-cell resolution is required for ...

Researchers are actively searching for ways to extend the survival benefit of targeted cancer therapies to prevent the possibility of highly resistant tumors. A new study led by researchers at the ...

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases like skin cancer, cells also have repair mechanisms that can fix ...

Researchers have now taken a step toward that vision of molecular systems that repair cells inside the human body. Molecular repair built from a patient’s own cells will eventually ferret out cancer, ...

University of Virginia School of Medicine researchers have discovered how cells that let us hear can repair themselves after being damaged, an insight that could benefit efforts to treat and prevent ...

Following an injury, such as a traumatic crush injury, the peripheral nervous system is itself often able to effectively regenerate. This regeneration capacity is mainly attributable to the Schwann ...

Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve ...

Salk researchers report they have discovered a protein called Mitf that mediates the repair function in the peripheral nervous systems of mice. The protein Mitf helps turn on the repair function of ...