St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

Dendritic cells occupy a pivotal role at the nexus of metabolism and immune regulation, employing distinct bioenergetic programmes to calibrate antigen uptake, processing and presentation. In their ...

A study led by researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has identified a mitochondrial checkpoint that enables dendritic cells to efficiently activate T ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells, the immune system's sentinels, in a "ready-to-respond" ...

Researchers identified a lymph node-mediated immune pathway that directed T cells into the brain in mouse models of tauopathy ...

Dendritic cells (DCs) in teleost fish are pivotal antigen-presenting cells that bridge the innate and adaptive arms of immunity. Morphologically and functionally analogous to their mammalian ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

Results show that eliminating dendritic cells from the lymph nodes wiped out elevated levels of T cells in mice, and slowed cognitive decline.

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

New research from Dana-Farber Cancer Institute scientists suggests that cyclin-dependent kinase 2 (CDK2) inhibitors, which ...

(MEMPHIS, Tenn. – April 02, 2026) St. Jude Children’s Research Hospital scientists have discovered how tumors disable immune “gatekeeper” cells that alert the rest of the immune system to the presence ...