Polycystic kidney disease (PKD) causes round, fluid-filled sacs called cysts to grow in your kidneys. These cysts can cause your kidneys to enlarge and function poorly. People with PKD can also ...

Autosomal dominant polycystic kidney disease (PKD) is a chronic and debilitating condition affecting over 12 million patients worldwide. PKD arises from mutations in the polycystin-1 (PC1) or PC2 ...

MIT researchers including Robert Croy (left) and Bogdan Fedeles have discovered that a drug they originally developed as a potential cancer treatment may also hold promise in treating autosomal ...

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

Polycystic kidney disease (PKD) is a common genetic disorder, and it's thought to affect over 12 million people every year. PKD causes fluid filled cysts to form in the kidney, causing pain and high ...

Discovering a lump can be alarming, but not all are dangerous. Cysts, typically fluid-filled and harmless, differ from ...

Liver cysts were found in over 80% of patients with ADPKD but were not associated with chronic kidney disease stage, Mayo classification, PKD1 or PKD2 genotype variant, liver enzyme levels, or quality ...

Share on Pinterest Researchers say sugar can affect cysts that may be a factor in a common type of kidney disease. Oliver Bunic/Bloomberg via Getty Images The research team cultivated organoids that ...