A combination of cryogenic electron microscopy and molecular simulations has been used to study the structure and dynamics of an enzyme called ACE.

A new study led by Stephen Withers from the University of British Columbia introduces a technique for engineering much more ...

Temperature and substrate availability constrain the activity of the extracellular enzymes that decompose and release nutrients from soil organic matter (SOM). Proteolytic enzymes are the primary ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates – an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...