To mark the 50 th anniversary of the discovery of the three nuclear RNA polymerases, we feature a collection of Perspective and Review pieces that narrate the history of eukaryotic transcription ...

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

The central dogma of molecular biology dictates that information flows from DNA into RNA into protein in living cells. Transcription, a major tenet of this dogma, is the process by which information ...

The regulation of mRNA transcription plays a key role in relaying signals from the environment and during development into the gene expression program of a cell. During transcription initiation, a ...

Transcription is the first step of gene expression, where a DNA sequence is copied into messenger RNA. In eukaryotes, transcription initiation starts with the assembly of the transcription ...