Am J Health Syst Pharm. 2006;63(5):419-430. During resorption, growth factors and proteins released from osteoblast precursors and bone stimulate the differentiation, chemotaxis, and proliferation of ...

There is a complex pathological relationship between diabetes and osteoporosis, two of the most common chronic diseases worldwide.

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an increased risk of fractures. Osteoclasts, the bone-resorbing cells, are widely ...

About 90% of patients with multiple myeloma (MM) develop severe bone disease, known as myeloma bone disease (MBD). This occurs due to the ability of MM cells to disrupt bone homeostasis, leading to ...

Researchers at Hiroshima University have discovered the mechanism underlying multifocal osteomyelitis in MSMD patients with poor response to IFN-γ. IFN-γ plays an inhibitory role in osteoclast ...