The Annals of Statistics publishes research papers of the highest quality reflecting the many facets of contemporary statistics. Primary emphasis is placed on importance and originality, not on ...

This is a preview. Log in through your library . Abstract A technique for single degree of freedom partitioning of canonical contrasts for prime level factorials with quantitative levels is reviewed.

Experimentation is a vital part of the scientific method. Most problems in science require observation of the system at work and experimentation to elucidate information about how the system works. In ...

A polypill comprising statins, multiple blood-pressure–lowering drugs, and aspirin has been proposed to reduce the risk of cardiovascular disease. Using a 2-by-2-by-2 factorial design, we randomly ...