The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

For decades, scientists viewed the genome of a newly fertilised egg as a structural 'blank slate' – a disordered tangle of DNA waiting for the embryo to 'wake up' and start reading its own genetic ...

Researchers have identified a physical process called “mitochondrial pearling” that explains how cells keep their ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

EPFL scientists have discovered that a simple shape change in mitochondria helps cells evenly distribute their mitochondrial ...

Plant cells host a variety of organelles segregated into distinct functional groups. Among those organelles, the nucleus, ...