HLA (Human Leukocyte Antigen) typing is important in organ transplantation protocols, as they determine the likelihood of rejection. The HLA system is little understood, however. In simple terms, the ...
The WHO Nomenclature Committee for Factors of the HLA System met during the 15th International Histocompatibility and Immunogenetics Workshop in Buzios, Brazil in September 2008. This update is an ...
Please provide your email address to receive an email when new articles are posted on . A link between condylomas, or genital warts, and the human leukocyte antigen system could suggest a genetic risk ...
Scientists from the Heidelberg Institute for Theoretical Studies (HITS), the German Cancer Research Center (DKFZ), the Heidelberg University Hospital and Heidelberg University have established ...
The human leukocyte antigen (HLA) system has an important role in the regulation of the immune system; the HLA recognizes cells as ‘non-self’ or ‘self’ to prevent the body from attacking its own cells ...
Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...
A 2026 narrative review links inherited HLA class I and class II variation to pediatric neuroblastoma susceptibility and selected outcomes, while finding that most associations remain unreplicated and ...
Researchers used CRISPR-Cas9 to knock out the TAPBP gene in human induced pluripotent stem cells, producing cardiomyocytes ...
Atellica HLA HLA Typing System hums away in a dimly lit transplant lab, its robotic arm sliding microplates with a soft clack instead of a tech manually juggling pipettes. The system targets ...
Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...
HLA testing has been a staple in transplantation since the recognition that antibodies, directed against lymphocytes, were associated with allograft failure. This seminal finding led to the discovery ...