When Iowa wins, they win big. That's exactly why ESPN Analytics gives them an 89.4% chance to beat MSU. Iowa dominated Rutgers in the second half and blew past both Wisconsin and Minnesota, with only the Golden Gophers game taking place at home. It'd be shocking if their game against the Spartans wasn't a repeat of October 25 vs. Minnesota.

Spartans face historic losing streak and potential rock bottom against Iowa. Can they avoid ignominy in Kinnick Stadium?

The Iowa Hawkeyes (6-4) square off against a conference opponent when they host the Michigan State Spartans (3-7) on Saturday, Nov. 22, 2025 at Kinnick Stadium in a Big Ten showdown. Date: Nov. 22

Iowa football plays Nebraska in Week 14 of the NCAA college football season. Here's info on where to watch, start time and betting odds.