Cells are a fundamental unit of biological organization, and identifying them in imaging data—cell segmentation—is a critical task for various cellular imaging experiments. Although deep learning ...
Tissue makeup depends on the local cellular microenvironment. Spatial single-cell genomics enables scalable and unbiased interrogation of these interactions. Here we introduce Nicheformer, a ...
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...