Nature

Assessment of pathogenic variation in gynecologic cancer genes in a national cohort

Hereditary gynecologic cancers include breast, ovarian, and endometrial cancer, as well as some other rare cancers of the female reproductive system 1, where a pathogenic variant, leading to a ...
ascopubs.org

Germline pathogenic variants in cancer predisposition genes and overall survival of women with breast cancer.

Association between type of BRCA1/2 pathogenic/likely pathogenic variants and outcome in young patients with breast cancer: Results from an international cohort study. This is an ASCO Meeting Abstract ...
ascopubs.org

Association between type of BRCA1/2 pathogenic/likely pathogenic variants and outcome in young patients with breast cancer: Results from an international cohort study.

Association of glucagon-like peptide 1 receptor agonists with cancer risk in obesity adults with and without diabetes: A target trial emulation study. This is an ASCO Meeting Abstract from the 2025 ...
Nature

Expanding the utility of variant effect predictions with phenotype-specific models

Current methods for variant effect prediction do not differentiate between pathogenic variants resulting in different disease outcomes and are restricted in application due to a focus on variants with ...