Ikoma, Japan – Rho GTPases have a crucial role in the orchestration of cell movements. Cells use Rho GTPases to coordinate cytoskeletal reorganization in dynamically changing environments. Among these ...

Rho GTPases Cdc42 and RacA share significant sequence homology and are conserved among eukaryotic species. These proteins act as molecular switches in various signal transduction pathways by cycling ...

Cytotoxic necrotizing factors (CNFs) are bacterial exotoxins that have attracted significant attention due to their ability to modify host cell functions by targeting Rho GTPases. These small, ...

This article and associated images are based on a poster originally authored by Oliver Carney, Louis Hodgson, and Carl Peters, and presented at ELRIG Drug Discovery 2025 in affiliation with BMG ...