The development of precise RNA-editing tools is essential for the advancement of RNA therapeutics. CRISPR (clustered regularly interspaced short palindromic repeats) PspCas13b is a programmable RNA ...
During DNA replication, the two new DNA strands are synthesized asymmetrically, with the leading strand synthesized in a continuous fashion and the lagging strand synthesized as a discontinuous series ...
Existing genome-wide methylation technologies provide coarse-grained resolution. Pellegrini wanted single-base data on a genome-wide scale. Pellegrini and his colleagues combined bisulfite conversion ...
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