Nat Clin Pract Neurol. 2008;4(3):159-169. A 3-year follow-up study of patients with MS treated with sodium channel blockers for neuropathic pain or other paroxysmal symptoms revealed adverse effects ...

PHILADELPHIA -- An oral, non-addictive sodium channel blocker safely relieved moderate-to-severe acute pain following surgery, according to phase III data that could support regulatory approval.

Blockade of voltage-gated sodium channels (NaChs) in pancreatic α cells has anti-diabetic effects, according to research published online May 8 in Diabetes. Arvinder K. Dhalla, Ph.D., of Gilead ...

Several studies examining the use of sodium-channel blockers in patients with multiple sclerosis are currently underway. Questions about the long-term effects of these agents in neuroinflammatory ...

Mutant Brown-Norway-Katholiek (muBN-Ka) rats are capable of producing kininogens in the liver, but cannot release them into the bloodstream, because of the point mutation of Ala163 to Thr in the ...

This story was originally published on BioPharma Dive. To receive daily news and insights, subscribe to our free daily BioPharma Dive newsletter. In the notoriously expensive business of drug ...

South Korea’s SK Biopharmaceuticals Co. Ltd. and Shanghai-based Ignis Therapeutic Co. Ltd. signed a ₩804 billion (US$58 million) licensing deal on April 18, granting the latter global rights to a ...

A new study on live tissue cells is the first to reveal how channels that allow sodium to enter into breast cancer cells enable tumours to grow and spread. The discovery adds to evidence which ...

Dr. Naccarelli answers the question: 'What Is Flecainide, How Does It Work?' — -- Question: I have been placed on an antiarrhythmic drug called flecainide for my heart rhythm problem. How does it ...

Nat Clin Pract Neurol. 2008;4(3):159-169. Despite the fact that phenytoin has been used successfully in the past to treat positive symptoms in patients with MS, the investigators at Yale University ...