Mechano-Growth Factor (MGF), often referred to as the IGF-1 Ec isoform (or IGF-1 Eb), is a splice variant of the insulin-like ...

Introduction: Normal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells exhibiting various degrees of maturation and differentiation. While cultured cell ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation — the process ...

From left to right: Aleixandre Rodrigo, Manuel Salmeron and Mariana Azevedo in the IBEC laboratories. Research led by Manuel Salmeron, ICREA Research Professor at the Institute for Bioengineering of ...

Recent studies have demonstrated that insulin-like growth factor-1 (IGF-I) modulates bone mesenchymal stem cell chondrogenic differentiation independent of transforming growth factor beta (TGF-β) ...

Small-cell lung cancer (SCLC) causes cells in lung tissue to mutate and grow uncontrollably. When these cells look different than healthy cells under a microscope, doctors call this poorly ...

Robert Mauck, PhD, from the University of Pennsylvania, discussed how aging and differentiation alter nuclear mechanobiology at the 2014 American Society of Bone and Mineral Research Conference in ...

In a recent study published in Cell, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages. They pursued a conceptual framework for better ...

Multipotent dental stem cells can give rise to various cell types and show potential for treating injuries, diabetes, and ...

Glucose is life's main energy source. But a new study reveals a surprising role as a master manipulator of tissue maturation, hinting at its importance in diabetes and cancer. The sugar glucose, which ...