PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

People with autosomal dominant polycystic kidney disease (ADPKD) are at a high risk of developing kidney failure during their lives. Although there are many strategies that can be used to help reduce ...

A new drug lowered blood pressure and improved kidney health markers in high-risk patients. Phase 3 trials will test its long-term effects. Preliminary research suggests that adding the new medication ...

Having PKD increases the risk of brain aneurysms. This is due to several factors, including the genetic aspects of PKD and its effect on blood pressure. Polycystic kidney disease (PKD) is a hereditary ...

A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious ...

For patients that are recently diagnosed with kidney cancer, it is important for them to do a number of different things.

Vertex has built its business on genetic medicines for cystic fibrosis, which generated almost $10 billion in revenues in 2023. Vertex looks forward to fully exploring Alpine's povetacicept's ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys are damaged and can’t filter blood effectively. This can eventually lead to a buildup of waste and fluid in the body. In ...

Please provide your email address to receive an email when new articles are posted on . The study reported elevated adjusted rates for four non-pulmonary complications in those with vs. without cystic ...