Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Alterations in DNA repair pathways are a hallmark of carcinogenesis. They result in genomic instability, promote the accumulation of mutations and tumorigenesis, and influence treatment response 1.

Homologous recombination (HR) and mismatch repair (MMR) defects are driver mutational imprints and actionable biomarkers in DNA repair-defective tumors. Although usually thought as mutually exclusive ...

Our DNA is under constant attack from many sources, including environmental pollutants, ultraviolet light, and radiation. Fortunately, cells have several major DNA repair systems that can fix this ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

Migrating newborn neurons suffer routine double-strand DNA breaks from physical stress during brain development.

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...