The human genetic code is fully mapped out, providing scientists with a blueprint of the DNA to identify genomic regions and their variations responsible for diseases. Traditional statistical tools ...

Scientists have now discovered why a mutation in a gene called TET2 is often implicated in disorders including diabetes, heart disease, stroke, inflammatory diseases, and certain types of cancer. This ...

Many statistical models and algorithms used by scientists can be imagined as a "black box." These models are powerful tools that give accurate predictions, but their internal workings are not easily ...

Precision medicine in GU cancers is evolving with biomarkers like BRCA1/2 mutations influencing PARP inhibitor use and pembrolizumab's tumor-agnostic approval for microsatellite instability. FGFR3 ...

Graduate student Hillary Layden studies transcriptional control of cancer in the lab of Scott Hiebert, Hortense B. Ingram Chair in Cancer Research and professor of biochemistry. Below, Layden shares ...

Genetic testing identifies germline mutations, while genomic testing analyzes somatic mutations in tumors, influencing treatment options. Broader testing criteria are expanding access to genetic ...

Figure 3. Docking of ADNP_Glu931Glyfs12 to the PTB protein. (A) The results of docking ADNP_Glu931Glyfs12 (light orange) to the PTB protein (PDB code 3DXC, navy blue) in the 934-941 amino acid region ...

A mutation in the KRAS gene may affect your treatment options and outlook with colorectal cancer. Researchers are looking into new treatments that can target KRAS mutations. Colorectal cancer occurs ...

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New study demonstrates how high-affinity B cells 'bank' their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design. A vaccine's ...

The PhD student with a background in physics, is not only focused on the performance of statistical models for genomic predictions but is also keen on understanding the underlying biological ...