An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Turning genes on and off is like flipping a light switch, controlling whether genes in a cell are active. When a gene is ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Professor Adam Paré's research identifies the fundamental mechanisms that mold tissues during animal development. On Wednesday, he will discuss epithelial remodeling during development.

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

If our genes are so similar, what really makes a eukaryote different from a prokaryote, or a human from E. coli? The answer lies in the difference in gene expression and regulation used. Regulation of ...

A gene-editing tool that can turn genes on and off like a light switch has been developed. Turning a gene on means activating ...