In the recent article, “Antisense Oligonucleotide Therapy for Calmodulinopathy,” we provided the first proof-of-concept in ...

The growing morbidity, mortality, and health care costs related to heart failure (HF) underscore the urgent need to prioritize its primary prevention. Whereas a risk-based approach for HF prevention ...

Elevated plasma levels of Lp(a) [lipoprotein(a)] are a causal risk factor for coronary heart disease and stroke in European individuals, but the causal relevance of Lp(a) for different stroke types ...

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The recent study by Bortolin et al, 1 “Antisense Oligonucleotide Therapy for Calmodulinopathy,” presents an innovative therapeutic strategy for rare inherited arrhythmia syndromes. By leveraging ...

Such findings were generally ignored because multiple epidemiological studies have demonstrated reduced cardiovascular disease (CVD) events with increasing levels of physical activity (PA). Randomized ...

ED indicates emergency department; CP, chest pain. Data were not reported for items left blank. Defined using creatine kinase-MB in all sources, except troponin was used in References 6 and 8.

Unlike CTA, NCCT is almost universally performed to diagnose ICH in the emergency department. NCCT biomarkers have the potential to become an inexpensive and readily available tool to stratify the ...

Our vision is to innovate and incorporate promising technologies to communicate freely available, high-priority, high-quality content, which accelerates scientific progress and advances heart and ...

In the 1960s and 1970s, large, descriptive autopsy studies were conducted, providing classic morphological features of intracranial arteries. Despite the importance of intracranial atherosclerosis to ...