Compared with age- and sex-matched controls in the general population, people with HIV were over four times more likely to ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the restraint of ...

Researchers hope that resetting these cells may help the immune system regain characteristics of healthier immune responses.

A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is ...

For some people, cancer immunotherapies are life-changing. These treatments can turn the body's own immune system against a tumor, either eliminating it or shrinking it enough to make surgery possible ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting ...

Medical advancements over the last several decades have made great strides in the treatment of HIV. Pharmaceutical treatments are able to contain and reduce a patient's viral load to the point where ...

Over the past decade, the Human Cell Atlas community has accomplished something that will define a generation of biology.

In a quest to provide more relevant translational data, traditional in vivo models join forces with new approach methodologies.