In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...

Learn more about eLife assessments Scientific progress depends on reliable and reproducible results. Progress can be accelerated when data are shared and re-analyzed to address new questions. Current ...

Excel has thousands of functions, but most people stick to the basics, like SUM and AVERAGE. While those work fine for simple tasks, there are three functions that handle more complex scenarios with ...

Recent advances in high-throughput microbiome profiling have generated expansive data sets that offer unprecedented ...

If Wenjun Zhang has her way, no one will ever have to brush or floss again. Zhang, a UC Berkeley professor of chemical and biomolecular engineering, is trying to distinguish the healthy bacteria in ...

We thank Dr. Jianzhi Zhang, Dr. Xionglei He, Dr. Weiwei Zhai, Shanshan Chen, Han Liu, Tianhan Wang, and three anonymous reviewers for valuable comments. This work was supported by the Strategic ...

Abstract: In this paper, an adaptive critic design with performance guarantee is established based on the discounted value iteration algorithm to settle with the optimal regulation problem for ...

Rollout of NativeLink and ProTrigger products for next-generation antibody conjugates, plus an ADC therapeutic discovery collaboration with a leading biotech, highlight early momentum PALO ALTO, Calif ...

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Viral infections pose a major threat to global health, causing severe pneumonia, meningitis, hepatitis, and fatal complications. Viruses are highly dependent on host cellular factors to complete their ...