USP17LA loss enhances T-cell function and anti-tumor activity in murine tumor models. Usp17la-deficient T cells exhibit ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

UCSF researchers designed a CAR T-cell therapy and combined it with an older class of diabetes drugs called ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

X™ T-Cell Transduction Sponge is honored in the Lab Research Tools category of the 2025 Top Innovations contest.

SciTech Development, Inc., a clinical-stage oncology company advancing its innovative nanotechnology-enabled cancer drug, ...

Made Scientific, a leading cell therapy contract development and manufacturing organization (CDMO) and Syenex, a synthetic biology company specializing in best-in-class targeted delivery technologies, ...

SciTech Development Inc., a clinical-stage oncology company in Detroit, has closed its Convertible Note Round No. 3 (CNR 3) ...

Amsbio is helping researchers fast-track CAR-T cell therapy development with a growing portfolio of experimental cell lines, ...