Wired

Basics: Vectors and Vector Addition

pre-reqs: trig Think of the following two things. Temperature and wind speed. These are two different things that you could measure, but there is one big difference. Wind speed has two parts to it - ...
Wired

How do you represent vectors?

Recently, I was talking about vectors. At that time, I had to stop and recall how I had been representing vectors. Ideally, I should stick with the same notation I used in Basics: Vectors and Vector ...
Nature

Transient blocking of both B7.1 (CD80) and B7.2 (CD86) in addition to CD40–CD40L interaction fully abrogates the immune response following systemic injection of adenovirus vector

Blockade of the CD40–CD40L and CD80/CD86–CD28 costimulatory pathways represents a strategy to inhibit the immune response against Ad vectors designed for gene therapy applications. Since most previous ...
Nature

Addition of adenoviral vector targeting of chemotherapy to the MUC-1/ecdCD40L VPPP vector prime protein boost vaccine prolongs survival of mice carrying growing subcutaneous ...

However, the use of systemic chemotherapy, delivered at the time of vaccination, could also diminish the TAA/ecdCD40L VPP vaccine-induced immune response due to the chemotherapy sensitivity of the TAA ...