Invasive epicardial coronary physiologic assessment is increasingly performed to evaluate the hemodynamic significance of ...

Background: Cardiovascular disease caused by atherosclerosis is responsible for 18 million deaths annually, highlighting a significant need for new medical therapies, especially for patients who are ...

Background: Observational studies have suggested that sodium-glucose cotransporter 2 inhibitors (SGLT2i) are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation ...

Background: Cardiovascular disease (CVD) prevalence is rising among younger women in the US. Hypertensive disorders of pregnancy (HDP) are early indicators of cardiovascular risk, yet it remains ...

eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are ...

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Background: The optimal antithrombotic treatment following transcatheter left atrial appendage closure (LAAC) remains to be determined. The objective of this trial was to compare anticoagulation and ...

Fifty years ago, in September 1975, the ischemic penumbra was discovered in a series of 4 pioneering experiments carried out in Lindsay Symons laboratory in London. This personal vignette gives an ...

The effects of both direct and reflexly induced increases in sympathetic activity on the blood flow to an extremity at rest and during muscular activity have been studied. When the O2 uptake of an ...

All manuscripts should conform to one of the below article types and authors should note the length restrictions and other eligibility criteria for each type of article. Word limits for each ...

eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are ...

The action of two pure veratrum alkaloids, veratridine and protoveratrine, in human hypertension is described for the first time. The vasodepressor reflex pathway involved in the response to these ...