Researchers have discovered how unstructured segments of surface proteins regulate the biological function of a cell. Their study, published in Nature Communications, sheds new light on the interplay ...
You will be redirected to our submission process. Lysosomes, historically viewed as simple degradative organelles, are now recognized as pivotal signaling hubs crucial for cellular homeostasis. A ...
Given the success of Volume I of this Research Topic, and how rapid the subject area is evolving, we are pleased to announce the launch of "GPCRs: Signal Transduction: Volume II" GPCRs are comprised ...
The authors investigate arrestin2-mediated CCR5 endocytosis in the context of clathrin and AP2 contributions. Using an extensive set of NMR experiments, and supported by microscopy and other ...
The Research Center for Traditional Chinese Medicine, Shanghai Institute of Infectious Diseases and Biosecurity, School of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, ...
GPCRs (G protein-coupled receptors), also known as 7 transmembrane domain receptors, are the largest receptor family in the human genome, with ≈800 members. GPCRs regulate nearly every aspect of human ...
The global G-protein coupled receptors market size surpassed US$ 3.86 in 2024, rise to US$ 4.06 billion in 2025, and is expected to hit around US$ 6.37 billion by 2034. The market is growing at a CAGR ...
Abstract: Parameter estimation of signal transduction pathway models is a challenging task as such models are normally nonlinear, high dimensional, and the measurement data is limited and corrupted by ...
Designated areas (white circles) were irradiated with blue light at specific frequencies (indicated in the top left of each panel) to examine chemotactic aggregation. A research team led by Dr.
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