Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

UC San Francisco scientists used CRISPRa to boost healthy SCN2A gene expression in mice, reducing seizures and restoring brain function in a severe neurodevelopmental disorder.

When I first did the hearing experiment on mice, it was so straightforward — I could see the connection right away between what we were testing and the bigger picture of hearing loss,” Kate Xie shared ...

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate cancer will benefit from adding hormone therapy to radiation after surgery - the ...

Pharmacogenomic testing can tell how a drug is likely to work in a certain person. But is it ready for rolling out to the wider population?

Doctors can order genetic tests for people at high risk of breast cancer, and insurance often covers those, Kamal says. For people without a clear genetic risk or who don't know their family health ...

Real-time PCR enables faster Mycoplasma detection to meet rigorous cell therapy safety standards and reduce quality control-related workflow delays.

Immunotherapy has transformed the treatment of cancer, yet many patients do not have response or lasting benefit. Strategies to overcome resistance remain of crucial importance. Oncolytic viruses ...