How cell and gene therapy developers can lessen the chances of receiving FDA complete response letters through the use of proactive chemistry, manufacturing, and controls strategies.

Vivek Subbiah, MD, considers artificial intelligence (AI) and comprehensive somatic and germline testing essential for guiding precision oncology and improving patient care.

Doctors can order genetic tests for people at high risk of breast cancer, and insurance often covers those, Kamal says. For people without a clear genetic risk or who don't know their family health ...

In honor of Breast Cancer Awareness Month, the TODAY show, with the help of breast cancer survivors Jill Martin and Sheryl Crow, hosted Pink Power, an event dedicated to encouraging viewers and fans ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

This study presents the important finding that lysosomal damage triggers inflammatory signaling through ubiquitination and the TAB-TAK1-IKK-NF-kB axis. The data obtained from the unbiased ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Loss of p300/CBP decreases the activity of ...

Research has uncovered a previously unknown, widespread role of ORC in regulating human cell gene expression. New work has revealed a much wider role for origin-recognition complex (ORC) in regulating ...

While the process via which different types of neurons are produced, also known as neurogenesis, has been the focus of numerous neuroscience studies, its genetic and biological underpinnings in humans ...

The arms and heads of opossums (pictured here one day before birth) and other marsupials develop faster than their legs and back bodies. Image credit: Sergio Menchero Fernandez/ Francis Crick ...