Invasive epicardial coronary physiologic assessment is increasingly performed to evaluate the hemodynamic significance of ...
Background: Cardiovascular disease caused by atherosclerosis is responsible for 18 million deaths annually, highlighting a significant need for new medical therapies, especially for patients who are ...
Risk stratification of patients with chest pain has traditionally focused on identifying obstructive coronary artery disease (CAD). Using this traditional approach, many symptomatic individuals are ...
The rapid development and integration of artificial intelligence (AI), including predictive, generative, and emerging agentic ...
Background: Observational studies have suggested that sodium-glucose cotransporter 2 inhibitors (SGLT2i) are associated with a lower risk of atrial fibrillation (AF) recurrence after catheter ablation ...
Missing data in clinical trials remains an ongoing concern. With the expansion of data privacy efforts and the consequent inability to contact trial participants for follow-up, the magnitude and ...
Background: Cardiovascular disease (CVD) prevalence is rising among younger women in the US. Hypertensive disorders of pregnancy (HDP) are early indicators of cardiovascular risk, yet it remains ...
Introduction: There is increasing use of digital health solutions in heart failure (HF), but few studies have demonstrated its impact on public healthcare systems in North America. The Continuum ...
Background: Metformin is not FDA-approved for prediabetes but it is being prescribed off-label for this condition. Per the American Diabetes Association (ADA), metformin “should be considered” for ...
At 19 years of age, a woman experiencing dyspnea on exertion was diagnosed with idiopathic pulmonary arterial hypertension. Pulmonary arterial hypertension–targeted drugs (oral beraprost, sildenafil, ...
A 68-year-old man presented to the emergency department with sudden-onset chest pain, which had been persistent for 8 hours. He had been experiencing exertional shortness of breath in the preceding ...
Coronary angiography remains an important modality to assess atherosclerotic coronary artery disease and to guide percutaneous coronary intervention. Intravascular ultrasound (IVUS) is an important ...
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