One protein mitigates Huntington’s disease while another one exacerbates it by regulating the huntingtin protein’s movement in neurons.

Zebrafish lacking a functional muscle clock showed signs of premature aging at two years. They were shorter, weighed less, swam less frequently and at slower speeds.

Weeks after an injection of stem cells delivered to the brain, 80% of patients had improved CSF biomarkers with no adverse effects.

The transition from preclinical development to clinical trials is a critical, with approximately 89% of drugs failing. Nearly half of these failures stem from unexpected and unmanageable human ...

Chromatography has long been a bioprocess cornerstone but many platforms today are struggling to keep up with scale, speed, ...

Recursion said it earned its latest milestone payout by identifying differentiated, oral small molecule leads against a target the company described as a high interest immune cell target in immunology ...

A first-in-human clinical trial tests a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers.

The genome incorporation mechanism for LINE-1, the only autonomously active retrotransposon in humans, leverages the cell ...

Zevaskyn won FDA approval upon Abeona’s second filing of a biologics license application (BLA) for the therapy.

Accurate genomic profiling is essential for clinical decision-making and optimizing treatment recommendations.

Researchers say GlycoCaging may offer a route to rescue promising drug candidates that currently show unacceptable systemic ...

Scientists identified broadly neutralizing antitoxin antibodies in blood from snake venom-exposed hyperimmune donor for ...