A last-minute injury could change everything as the Tennessee Titans head to San Francisco.

For the first time in years, the Tennessee Titans have a chance to win back-to-back games.

There are six keys to the Tennessee Titans getting a win over the San Francisco 49ers in Week 15.

The Tennessee Titans and the San Francisco 49ers meet Sunday in Week 15 in Santa Clara, California, with kickoff slated for 4 ...

The Tennessee Titans dipped into their practice squad to add some reinforcements for their Week 15 matchup with the San Francisco 49ers.

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to ...

The Tennessee Titans face some questions along their offensive line, with three starters questionable for their Week 15 ...

Tennessee (2-11) at San Francisco (9-4) Sunday, 4:25 p.m. EST, Fox. BetMGM NFL Odds: 49ers by 12 1/2. Against the spread: Titans 6-7; 49ers 8-5. Series record: 49ers lead 9-6. Last meeting: Titans ...

The 49ers (9-4) take on No. 1 overall draft pick Cam Ward and the Tennessee Titans (2-11) on Sunday at Levi’s Stadium.

Find single game tickets to the San Francisco 49ers vs. Tennessee Titans NFL Week 15 matchup on Sunday, Dec. 14, 2025 at Levi ...

NFL Week 15 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Tennessee Titans ...