The ATP-Synthase in action: Protons (Yellow) go from the high concentration side (below) to the side with lower concentration. They do that by binding to the transmembrane portion of the ATP-Synthase. However, the place where the Protons enter and where they leave are in different locations. Therefore, the transmembrane portion of the ATP-Synthase has to rotate to bring the protons from one side to the other. The rotating motion of parts of the protein causes the non-rotating subunits to deform
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ATP synthase is a large enzyme found in the membranes of mitochondria, chloroplasts, and many bacteria. Its job is to make ATP (adenosine triphosphate), which is the main energy-carrying molecule used by cells. It works a bit like a molecular turbine. Protons (H⁺ ions) flow through part of the enzyme, driven by a concentration gradient across the membrane. This flow of protons causes part of ATP synthase to spin, and that spinning motion drives the joining of ADP (adenosine diphosphate) and inor
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